Digestive histology 10- Large intestine

Digestive histology 10- Large intestine


– All right.
The large intestine, we are not breaking it down
into its parts. We’re just looking at it
in general. And I’m going to tell you
how I tell if I’m in the large intestine. And it’s a relative feature. Most of these features are
relative, which means that’s one of the reasons
why I think histology is frustrating for people
because it is relative. Depending on the critter
that you pick, how long are the villi? How many glands do you see? Are there really billions of
Peyer’s patches like what you would expect? Or are there fewer
Peyer’s patches? And that’s just
normal variation. You’re going to see some
differences like that. In the large intestine, you are
going–you’re going to see lymphatic nodules. You’re just not going to see
billions of them. And the key that we’re going to
look for is goblet cells. Goblet cells in the epithelial
tissue. Why? Just think on that little
functional problem for a second. Like why would we have billions
of goblet cells in your large intestine? Remember those goblet cells
they look a little something, something like this. And what did they do? They’re embedded in with all the rest of the simple
columnar epithelium. Yeah. This is actually a really
pretty drawing right now so I’m going to keep going. What do they make?
Holy mucus barfage. Mucus. You are absorbing water
in the large intestine. You’re sucking the water out
of your doo-doo. And if you do not want your
doo-doo to get stuck in there, you better make some mucus so it
gets a little slippery so you can get it out. Right? Makes complete functional sense
why we would see such a structure
in the large intestine. The last piece of histology that
we have is the pancreas. We’re going to look at
pancreatic histology as well and hopefully it will be
relatively easy to do.

8 thoughts on “Digestive histology 10- Large intestine

  1. Thank you, for sharing your beautiful knowledge and your strong energy the way you explaining these difficult subject.

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